CYP3A7 Polyclonal Antibody

Rabbit Anti-CYP3A7 Polyclonal Antibody

Product Specifications

Background

CYP3A7 encodes a member of the cytochrome P450 superfamily of enzymes, which participate in drug metabolism and the synthesis of cholesterol, steroids and other lipids. This enzyme hydroxylates testosterone and dehydroepiandrosterone 3-sulphate, which is involved in the formation of estriol during pregnancy. CYP3A7 is part of a cluster of related genes on chromosome 7q21. Naturally-occurring readthrough transcription occurs between this gene and the downstream CYP3A51P pseudogene and is represented by GeneID: 100861540.

CAS Number

9007-83-4

Product Name Alternative

CYP3A7; Cytochrome P450 3A7; CYPIIIA7; Cytochrome P450-HFLA

Gene ID

1551

Accession Number

P24462

Reactivity

Human

Immunogen

Synthesized peptide derived from the Internal region of human CYP3A7 at AA rangle: 200-280

Clonality

Polyclonal

Tag

Cytochrome P450 3A7

Applications

WB, ELISA

Purification Method

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration

1 mg/ml

Molecular Weight

50kD

Precautions

The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.

Shipping Conditions

Gel pack with blue ice.

Storage Conditions

Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Notes

CYP3A7 Polyclonal Antibody detects endogenous levels of CYP3A7 protein.

Observed Molecular Weight

Formulation

Liquid solution

Buffer pH

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Applications Notes

Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-1:2000; ELISA 1:20000; Not yet tested in other applications.