CYP2A6/7 Polyclonal Antibody

Rabbit Anti-CYP2A6/7 Polyclonal Antibody

Product Specifications

Background

CYP2A7 encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. Cytochrome P450 2A7 localizes to the endoplasmic reticulum; its substrate has not yet been determined. CYP2A7, which produces two transcript variants, is part of a large cluster of cytochrome P450 genes from the CYP2A, CYP2B and CYP2F subfamilies on chromosome 19q.

CAS Number

9007-83-4

Product Name Alternative

CYP2A7; Cytochrome P450 2A7; CYPIIA7; Cytochrome P450 IIA4

Gene ID

1549

Accession Number

P20853

Reactivity

Human

Immunogen

Synthesized peptide derived from the Internal region of human CYP2A6/7 at AA rangle: 310-390

Clonality

Polyclonal

Tag

Cytochrome P450 2A7

Applications

IHC, IF, ELISA

Purification Method

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration

1 mg/ml

Precautions

The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.

Shipping Conditions

Gel pack with blue ice.

Storage Conditions

Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Notes

CYP2A6/7 Polyclonal Antibody detects endogenous levels of CYP2A6/7 protein.

Formulation

Liquid solution

Buffer pH

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Applications Notes

Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: IHC 1:100-1:300; ELISA 1:40000; IF 1:50-200