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ACTR-IC Polyclonal Antibody

Rabbit Anti-ACTR-IC Polyclonal Antibody

Product Specifications

Background

ACVR1C is a type I receptor for the TGFB (see MIM 190180) family of signaling molecules. Upon ligand binding, type I receptors phosphorylate cytoplasmic SMAD transcription factors, which then translocate to the nucleus and interact directly with DNA or in complex with other transcription factors (Bondestam et al. 2001 [PubMed 12063393]) .

CAS Number

9007-83-4

Product Name Alternative

ACVR1C; ALK7; Activin receptor type-1C; Activin receptor type IC; ACTR-IC; Activin receptor-like kinase 7; ALK-7

Gene ID

130399

Accession Number

Q8NER5

Reactivity

Human, Mouse, Rat

Immunogen

Synthesized peptide derived from the Internal region of human ACTR-IC at AA rangle: 180-260

Clonality

Polyclonal

Tag

Activin receptor type-1C

Applications

IHC, IF, ELISA

Purification Method

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration

1 mg/ml

Precautions

The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.

Shipping Conditions

Gel pack with blue ice.

Storage Conditions

Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Notes

ACTR-IC Polyclonal Antibody detects endogenous levels of ACTR-IC protein.

Formulation

Liquid solution

Buffer pH

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Applications Notes

Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: IHC 1:100-1:300; IF 1:200-1:1000; ELISA 1:20000; Not yet tested in other applications.

Other Product Names

ACVR1C; ALK7; Activin receptor type-1C; Activin receptor type IC; ACTR-IC; Activin receptor-like kinase 7; ALK-7

Tested Applications

WB, IHC, IF, IP, ELISA

Host or Source

Rabbit

Accession Number URL

http://www.uniprot.org/uniprot/Q8NER5

Isotype

Rabbit IgG

Available Sizes

Frequently Asked Questions

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