COL11A1 Polyclonal Antibody

Rabbit Anti-COL11A1 Polyclonal Antibody

Product Specifications

Background

COL11A1 encodes one of the two alpha chains of type XI collagen, a minor fibrillar collagen. Type XI collagen is a heterotrimer but the third alpha chain is a post-translationally modified alpha 1 type II chain. Mutations in this gene are associated with type II Stickler syndrome and with Marshall syndrome. A single-nucleotide polymorphism in this gene is also associated with susceptibility to lumbar disc herniation. Multiple transcript variants have been identified for this gene.

CAS Number

9007-83-4

Product Name Alternative

COL11A1; COLL6; Collagen alpha-1 (XI) chain

Gene ID

1301

Accession Number

P12107

Reactivity

Human, Mouse

Immunogen

Synthesized peptide derived from the Internal region of human COL11A1 at AA rangle: 550-630

Clonality

Polyclonal

Tag

Collagen alpha-1 (XI) chain

Applications

WB, IHC, IF, ELISA

Purification Method

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration

1 mg/ml

Molecular Weight

181kD

Precautions

The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.

Shipping Conditions

Gel pack with blue ice.

Storage Conditions

Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Notes

COL11A1 Polyclonal Antibody detects endogenous levels of COL11A1 protein.

Observed Molecular Weight

181

Formulation

Liquid solution

Buffer pH

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Applications Notes

Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-1:2000; IHC: 1:100-300; ELISA 1:20000; IF 1:100-300; Not yet tested in other applications.