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COL7A1 Polyclonal Antibody

Rabbit Anti-COL7A1 Polyclonal Antibody

Product Specifications

Background

COL7A1 encodes the alpha chain of type VII collagen. The type VII collagen fibril, composed of three identical alpha collagen chains, is restricted to the basement zone beneath stratified squamous epithelia. It functions as an anchoring fibril between the external epithelia and the underlying stroma. Mutations in this gene are associated with all forms of dystrophic epidermolysis bullosa. In the absence of mutations, however, an acquired form of this disease can result from an autoimmune response made to type VII collagen.

CAS Number

9007-83-4

Product Name Alternative

COL7A1; Collagen alpha-1 (VII) chain; Long-chain collagen; LC collagen

Gene ID

1294

Accession Number

Q02388

Reactivity

Human, Mouse

Immunogen

Synthesized peptide derived from the Internal region of human COL7A1 at AA rangle: 1810-1890

Clonality

Polyclonal

Tag

Collagen alpha-1 (VII) chain

Applications

IHC, IF, ELISA

Purification Method

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration

1 mg/ml

Precautions

The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.

Shipping Conditions

Gel pack with blue ice.

Storage Conditions

Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Notes

COL7A1 Polyclonal Antibody detects endogenous levels of COL7A1 protein.

Formulation

Liquid solution

Buffer pH

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Applications Notes

Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: IHC 1:100-1:300; IF 1:200-1:1000; ELISA 1:5000; Not yet tested in other applications.

Other Product Names

COL7A1; Collagen alpha-1 (VII) chain; Long-chain collagen; LC collagen

Tested Applications

WB, IHC, IF, IP, ELISA

Host or Source

Rabbit

Accession Number URL

http://www.uniprot.org/uniprot/Q02388

Isotype

Rabbit IgG

Available Sizes

Frequently Asked Questions

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