MI-503
Product Specifications
UNSPSC Description
MI-503 is a highly potent and orally bioavailable small molecule inhibitor of the menin-mLL interaction.
Target Antigen
Epigenetic Reader Domain
Type
Reference compound
Related Pathways
Epigenetics
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/MI-503.html
Solubility
DMSO : 25 mg/mL (ultrasonic)
Smiles
FC(F)(F)CC(S1)=CC2=C1N=CN=C2NC3CCN(CC4=CC=C(N(CC5=CNN=C5)C(C#N)=C6)C6=C4C)CC3
Molecular Weight
564.63
References & Citations
[1]Borkin D, et al. Pharmacologic inhibition of the Menin-MLL interaction blocks progression of MLL leukemia in vivo. Cancer Cell. 2015 Apr 13;27(4):589-602.
Shipping Conditions
Room Temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-16925/MI-503-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-16925/MI-503-SDS-MedChemExpress.pdf
Clinical Information
No Development Reported
CAS Number
1857417-13-0
Available Sizes
Curated Selection
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