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GBP5 Polyclonal Antibody

Rabbit Anti-GBP5 Polyclonal Antibody

Product Specifications

Background

GBP5 (Guanylate Binding Protein 5) is a Protein Coding gene. Diseases associated with GBP5 include chronic active epstein-barr virus infection. Among its related pathways are Immune System and Interferon gamma signaling. GO annotations related to this gene include identical protein binding and GTPase activity. An important paralog of this gene is GBP7. s an activator of NLRP3 inflammasome assembly, plays a role in innate immunity and inflammation. Promotes selective NLRP3 inflammasome assembly in response to microbial and soluble, but not crystalline, agents (PubMed: 22461501) . Hydrolyzes GTP, but in contrast to other family members, does not produce GMP (PubMed: 20180847) .

CAS Number

9007-83-4

Product Name Alternative

GBP5; Guanylate-binding protein 5; GBP-TA antigen; GTP-binding protein 5; GBP-5; Guanine nucleotide-binding protein 5

Gene ID

115362

Accession Number

Q96PP8

Reactivity

Human, Mouse

Immunogen

Synthesized peptide derived from the Internal region of human GBP5

Clonality

Polyclonal

Tag

Guanylate-binding protein 5

Applications

IHC, IF, WB, ELISA

Purification Method

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration

1 mg/ml

Molecular Weight

66kD

Precautions

The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.

Shipping Conditions

Gel pack with blue ice.

Storage Conditions

Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Notes

GBP5 Polyclonal Antibody detects endogenous levels of GBP5 protein.

Observed Molecular Weight

66

Formulation

Liquid solution

Buffer pH

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Applications Notes

Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000; IHC 1:100-1:300; ELISA 1:20000; IF 1:50-200

Other Product Names

GBP5; Guanylate-binding protein 5; GBP-TA antigen; GTP-binding protein 5; GBP-5; Guanine nucleotide-binding protein 5

Tested Applications

WB, IHC, IF, IP, ELISA

Host or Source

Rabbit

Accession Number URL

http://www.uniprot.org/uniprot/Q96PP8

Isotype

Rabbit IgG

Available Sizes

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