Histamine H3 Receptor Polyclonal Antibody

Rabbit Anti-Histamine H3 Receptor Polyclonal Antibody

Product Specifications

Background

Histamine is a ubiquitous messenger molecule released from mast cells, enterochromaffin-like cells, and neurons. Its various actions are mediated by histamine receptors H1, H2, H3 and H4. HRH3 encodes one of the histamine receptors (H3) which belongs to the family 1 of G protein-coupled receptors. It is an integral membrane protein and can regulate neurotransmitter release. This receptor can also increase voltage-dependent calcium current in smooth muscles and innervates the blood vessels and the heart in cardiovascular system.

CAS Number

9007-83-4

Product Name Alternative

HRH3; GPCR97; Histamine H3 receptor; H3R; HH3R; G-protein coupled receptor 97

Gene ID

11255

Accession Number

Q9Y5N1

Reactivity

Human, Mouse, Rat

Immunogen

Synthesized peptide derived from the Internal region of human Histamine H3 Receptor at AA rangle: 260-340

Clonality

Polyclonal

Tag

Histamine H3 receptor

Applications

WB, IHC, IF, ELISA

Purification Method

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration

1 mg/ml

Molecular Weight

49kD

Precautions

The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.

Shipping Conditions

Gel pack with blue ice.

Storage Conditions

Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Notes

Histamine H3 Receptor Polyclonal Antibody detects endogenous levels of Histamine H3 Receptor protein.

Observed Molecular Weight

Formulation

Liquid solution

Buffer pH

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Applications Notes

Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-1:2000; IHC 1:100-1:300; IF 1:200-1:1000; ELISA 1:5000; Not yet tested in other applications.