Tert-Butyl 3- (2-iodoethoxy) propanoate

Tert-Butyl 3- (2-iodoethoxy) propanoate is a PROTAC linker, which refers to the PEG composition. tert-Butyl 3- (2-iodoethoxy) propanoate can be used in the synthesis of PROTAC FAK degrader 1 (HY-119932) [1].

Product Specifications

CAS Number

[2296723-16-3]

UNSPSC

12352211

Hazard Statement

H302, H315, H319, H335

Target

PROTAC Linkers

Type

Reference compound

Related Pathways

PROTAC

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/tert-butyl-3-2-iodoethoxy-propanoate.html

Purity

95.0

Smiles

O=C(OC(C)(C)C)CCOCCI

Molecular Formula

C9H17IO3

Molecular Weight

300.13

Precautions

H302, H315, H319, H335

References & Citations

[1]Cromm PM, et al. Addressing Kinase-Independent Functions of Fak via PROTAC-Mediated Degradation. J Am Chem Soc. 2018 Dec 12;140 (49) :17019-17026.

Shipping Conditions

Room Temperature

Storage Conditions

4°C (Powder, protect from light)

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Isoform

PEG Linkers

Available Sizes

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