Tert-Butyl 3- (2-iodoethoxy) propanoate
Tert-Butyl 3- (2-iodoethoxy) propanoate is a PROTAC linker, which refers to the PEG composition. tert-Butyl 3- (2-iodoethoxy) propanoate can be used in the synthesis of PROTAC FAK degrader 1 (HY-119932) [1].
Product Specifications
CAS Number
[2296723-16-3]
UNSPSC
12352211
Hazard Statement
H302, H315, H319, H335
Target
PROTAC Linkers
Type
Reference compound
Related Pathways
PROTAC
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/tert-butyl-3-2-iodoethoxy-propanoate.html
Purity
95.0
Smiles
O=C(OC(C)(C)C)CCOCCI
Molecular Formula
C9H17IO3
Molecular Weight
300.13
Precautions
H302, H315, H319, H335
References & Citations
[1]Cromm PM, et al. Addressing Kinase-Independent Functions of Fak via PROTAC-Mediated Degradation. J Am Chem Soc. 2018 Dec 12;140 (49) :17019-17026.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, protect from light)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
PEG Linkers
Available Sizes
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