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Dkk-1 Polyclonal Antibody

Rabbit Anti-Dkk-1 Polyclonal Antibody

Product Specifications

Background

DKK1 encodes dickkopf WNT signaling pathway inhibitor 1 that is a member of the dickkopf family. It is a secreted protein with two cysteine rich regions and is involved in embryonic development through its inhibition of the WNT signaling pathway. Elevated levels of DKK1 in bone marrow plasma and peripheral blood is associated with the presence of osteolytic bone lesions in patients with multiple myeloma.

CAS Number

9007-83-4

Product Name Alternative

DKK1; Dickkopf-related protein 1; Dickkopf-1; Dkk-1; hDkk-1; SK

Gene ID

22943

Accession Number

O94907

Reactivity

Human, Mouse, Rat

Immunogen

Synthesized peptide derived from the C-terminal region of human Dkk-1

Clonality

Polyclonal

Tag

Dickkopf-related protein 1

Applications

WB, IHC, IF, ELISA

Purification Method

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration

1 mg/ml

Molecular Weight

29kD

Precautions

The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.

Shipping Conditions

Gel pack with blue ice.

Storage Conditions

Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Notes

Dkk-1 Polyclonal Antibody detects endogenous levels of Dkk-1 protein.

Product Datasheet

https://www.abbkine.com/datasheet/ABP53293.pdf

Observed Molecular Weight

29

Formulation

Liquid solution

Buffer pH

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Applications Notes

Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-1:2000; IHC: 1:100-1:300; ELISA 1:10000; IF 1:50-200

Other Product Names

DKK1; Dickkopf-related protein 1; Dickkopf-1; Dkk-1; hDkk-1; SK

Tested Applications

WB, IHC, IF, IP, ELISA

Host or Source

Rabbit

Accession Number URL

http://www.uniprot.org/uniprot/O94907

Isotype

Rabbit IgG

Available Sizes

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