Flt3-L Polyclonal Antibody

Rabbit Anti-Flt3-L Polyclonal Antibody

Product Specifications

Background

Dendritic cells (DCs) provide the key link between innate and adaptive immunity by recognizing pathogens and priming pathogen-specific immune responses. FLT3LG controls the development of DCs and is particularly important for plasmacytoid DCs and CD8 (see MIM 186910) -positive classical DCs and their CD103 (ITGAE; MIM 604682) -positive tissue counterparts (summary by Sathaliyawala et al. 2010 [PubMed: 20933441]) .

CAS Number

9007-83-4

Product Name Alternative

FLT3LG; Fms-related tyrosine kinase 3 ligand; Flt3 ligand; Flt3L; SL cytokine

Gene ID

2323

Accession Number

P49771

Reactivity

Human, Mouse

Immunogen

Synthesized peptide derived from the C-terminal region of human Flt3-L

Clonality

Polyclonal

Tag

Fms-related tyrosine kinase 3 ligand

Applications

WB, ELISA

Purification Method

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration

1 mg/ml

Molecular Weight

26kD

Precautions

The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.

Shipping Conditions

Gel pack with blue ice.

Storage Conditions

Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Notes

Flt3-L Polyclonal Antibody detects endogenous levels of Flt3-L protein.

Observed Molecular Weight

Formulation

Liquid solution

Buffer pH

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Applications Notes

Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-1:2000; ELISA 1:20000; Not yet tested in other applications.