EP1 Polyclonal Antibody

Rabbit Anti-EP1 Polyclonal Antibody

Product Specifications

Background

Prostaglandin E2 receptor EP1 subtype encoded by PTGER1 is a member of the G protein-coupled receptor family. This protein is one of four receptors identified for prostaglandin E2 (PGE2) . Through a phosphatidylinositol-calcium second messenger system, G-Q proteins mediate this receptor's activity. Knockout studies in mice suggested a role of this receptor in mediating algesia and in regulation of blood pressure. Studies in mice also suggested that this gene may mediate adrenocorticotropic hormone response to bacterial endotoxin.

CAS Number

9007-83-4

Product Name Alternative

PTGER1; Prostaglandin E2 receptor EP1 subtype; PGE receptor EP1 subtype; PGE2 receptor EP1 subtype; Prostanoid EP1 receptor

Gene ID

5731

Accession Number

P34995

Reactivity

Human, Rat, Mouse

Immunogen

Synthesized peptide derived from the Internal region of human EP1

Clonality

Polyclonal

Tag

Prostaglandin E2 receptor EP1 subtype

Applications

WB, ELISA

Purification Method

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration

1 mg/ml

Molecular Weight

44kD

Precautions

The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.

Shipping Conditions

Gel pack with blue ice.

Storage Conditions

Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Notes

EP1 Polyclonal Antibody detects endogenous levels of EP1 protein.

Observed Molecular Weight

Formulation

Liquid solution

Buffer pH

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Applications Notes

Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-1:2000; ELISA 1:20000; Not yet tested in other applications.