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EKLF Polyclonal Antibody

Rabbit Anti-EKLF Polyclonal Antibody

Product Specifications

Background

KLF1 encodes a hematopoietic-specific transcription factor that induces high-level expression of adult beta-globin and other erythroid genes. The zinc-finger protein binds to the DNA sequence CCACACCCT found in the beta hemoglobin promoter. Heterozygous loss-of-function mutations in this gene result in the dominant In (Lu) blood phenotype.

CAS Number

9007-83-4

Product Name Alternative

KLF1; EKLF; Krueppel-like factor 1; Erythroid krueppel-like transcription factor; EKLF

Gene ID

10661

Accession Number

Q13351

Reactivity

Human, Mouse

Immunogen

Synthesized peptide derived from human EKLF around the non-acetylation site of K274

Clonality

Polyclonal

Tag

Krueppel-like factor 1

Applications

WB, ELISA

Field of Research

Cancer#Signal Transduction

Purification Method

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration

1 mg/ml

Molecular Weight

38kD

Precautions

The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.

Shipping Conditions

Gel pack with blue ice.

Storage Conditions

Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Notes

EKLF Polyclonal Antibody detects endogenous levels of EKLF protein only when non-acetylation at K274.

Observed Molecular Weight

38

Formulation

Liquid solution

Buffer pH

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Applications Notes

Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-1:2000; ELISA 1:20000; Not yet tested in other applications.

Other Product Names

KLF1; EKLF; Krueppel-like factor 1; Erythroid krueppel-like transcription factor; EKLF

Tested Applications

WB, IHC, IF, IP, ELISA

Host or Source

Rabbit

Accession Number URL

http://www.uniprot.org/uniprot/Q13351

Isotype

Rabbit IgG

Available Sizes

Frequently Asked Questions

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