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NTE Polyclonal Antibody

Rabbit Anti-NTE Polyclonal Antibody

Product Specifications

Background

PNPLA6 encodes a phospholipase that deacetylates intracellular phosphatidylcholine to produce glycerophosphocholine. It is thought to function in neurite outgrowth and process elongation during neuronal differentiation. The protein is anchored to the cytoplasmic face of the endoplasmic reticulum in both neurons and non-neuronal cells. Mutations in this gene result in autosomal recessive spastic paraplegia, and the protein is the target for neurodegeneration induced by organophosphorus compounds and chemical warfare agents. Multiple transcript variants encoding different isoforms have been found for this gene.

CAS Number

9007-83-4

Product Name Alternative

PNPLA6; NTE; Neuropathy target esterase; Patatin-like phospholipase domain-containing protein 6

Gene ID

10908

Accession Number

Q8IY17

Reactivity

Human, Mouse, Rat

Immunogen

Synthesized peptide derived from the Internal region of human NTE

Clonality

Polyclonal

Tag

Neuropathy target esterase

Applications

WB, IHC, IF, ELISA

Purification Method

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration

1 mg/ml

Molecular Weight

150kD

Precautions

The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.

Shipping Conditions

Gel pack with blue ice.

Storage Conditions

Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Notes

NTE Polyclonal Antibody detects endogenous levels of NTE protein.

Product Datasheet

https://www.abbkine.com/datasheet/ABP53094.pdf

Observed Molecular Weight

150

Formulation

Liquid solution

Buffer pH

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Applications Notes

Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-1:2000; IHC: 1:100-1:300; ELISA 1:20000; IF 1:50-200

Other Product Names

PNPLA6; NTE; Neuropathy target esterase; Patatin-like phospholipase domain-containing protein 6

Tested Applications

WB, IHC, IF, IP, ELISA

Host or Source

Rabbit

Accession Number URL

http://www.uniprot.org/uniprot/Q8IY17

Isotype

Rabbit IgG

Available Sizes

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