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ET-1 Polyclonal Antibody

Rabbit Anti-ET-1 Polyclonal Antibody

Product Specifications

Background

EDN1 encodes a preproprotein that is proteolytically processed to generate a secreted peptide that belongs to the endothelin/sarafotoxin family. This peptide is a potent vasoconstrictor and its cognate receptors are therapeutic targets in the treatment of pulmonary arterial hypertension. Aberrant expression of this gene may promote tumorigenesis. Alternative splicing results in multiple transcript variants.

Product Name Alternative

EDN1; Endothelin-1; Preproendothelin-1; PPET1

Gene ID

1906

Accession Number

P05305

Reactivity

Human, Rat, Mouse

Immunogen

Synthesized peptide derived from the Internal region of human ET-1

Clonality

Polyclonal

Tag

Endothelin-1

Applications

WB, IHC, IF, ELISA

Purification Method

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration

1 mg/ml

Molecular Weight

25kD

Precautions

The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.

Shipping Conditions

Gel pack with blue ice.

Storage Conditions

Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Notes

ET-1 Polyclonal Antibody detects endogenous levels of ET-1 protein.

Product Datasheet

https://www.abbkine.com/datasheet/ABP52878.pdf

Observed Molecular Weight

25

Formulation

Liquid solution

Buffer pH

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Applications Notes

Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: IHC: 100-300; WB 1:500-1:2000; ELISA 1:20000; IF 1:50-200

Other Product Names

EDN1; Endothelin-1; Preproendothelin-1; PPET1

Tested Applications

WB, IHC, IF, IP, ELISA

Host or Source

Rabbit

Accession Number URL

http://www.uniprot.org/uniprot/P05305

CAS Number

9007-83-4

Isotype

Rabbit IgG

Available Sizes

Curated Selection

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