PAOX Polyclonal Antibody

PAOX (Polyamine Oxidase (Exo-N4-Amino) ) is a Protein Coding gene. Among its related pathways are Metabolism and cytochrome P450. Gene Ontology (GO) annotations related to this gene include receptor binding and polyamine oxidase activity. An important paralog of this gene is KDM1B. Flavoenzyme which catalyzes the oxidation of N (1) -acetylspermine to spermidine and is thus involved in the polyamine back-conversion. Can also oxidize N (1) -acetylspermidine to putrescine. Substrate specificity: n (1) -acetylspermine = N (1) -acetylspermidine > N (1), N (12) -diacylspermine >> spermine. Does not oxidize spermidine. Plays an important role in the regulation of polyamine intracellular concentration and has the potential to act as a determinant of cellular sensitivity to the antitumor polyamine analogs.

The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.

Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-1:2000; IHC: 1:100-300; ELISA 1:40000; IF 1:50-200