FPL 14294

FPL 14294 is a intranasally active anorectic agent and a cholecystokinin octapeptide (CCK) analog with enhanced metabolic stability. FPL 14294 induces satiety in many species and can be utilized in relevant research[1].

Product Specifications

CAS Number

[154132-95-3]

Product Name Alternative

ARL 14294

UNSPSC

12352005

Target

Cholecystokinin Receptor

Type

Reference compound

Related Pathways

GPCR/G Protein; Neuronal Signaling

Applications

Metabolism-protein/nucleotide metabolism

Field of Research

Metabolic Disease

Assay Protocol

https://www.medchemexpress.com/fpl-14294.html

Smiles

NC([C@H](CC1=CC=CC=C1)N(C)C([C@H](CC(O)=O)NC([C@H](CCSC)NC([C@@H](NC(CNC([C@H](CCSC)NC(CC2=CC=C(C=C2)OS(=O)(O)=O)=O)=O)=O)CC3=CNC4=CC=CC=C34)=O)=O)=O)=O

Molecular Formula

C45H56N8O13S3

Molecular Weight

1013.17

References & Citations

[1]Simmons RD, et al. FPL 14294: a novel CCK-8 agonist with potent intranasal anorectic activity in the rat. Pharmacol Biochem Behav. 1994 Mar;47 (3) :701-8.