XRCC4 Polyclonal Antibody

Rabbit Anti-XRCC4 Polyclonal Antibody

Product Specifications

Background

DNA repair protein XRCC4 encoded by XRCC4 functions together with DNA ligase IV and the DNA-dependent protein kinase in the repair of DNA double-strand breaks. This protein plays a role in both non-homologous end joining and the completion of V (D) J recombination. Mutations in this gene can cause short stature, microcephaly, and endocrine dysfunction (SSMED) . Alternative splicing generates several transcript variants.

CAS Number

9007-83-4

Product Name Alternative

XRCC4; DNA repair protein XRCC4; X-ray repair cross-complementing protein 4

Gene ID

7518

Accession Number

Q13426

Reactivity

Human, Mouse

Immunogen

Synthesized peptide derived from the C-terminal region of human XRCC4 at AA range: 230-310

Clonality

Polyclonal

Tag

DNA repair protein XRCC4

Applications

WB, ELISA

Purification Method

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration

1 mg/ml

Molecular Weight

40kD

Precautions

The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.

Shipping Conditions

Gel pack with blue ice.

Storage Conditions

Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Notes

XRCC4 Polyclonal Antibody detects endogenous levels of XRCC4 protein.

Observed Molecular Weight

Formulation

Liquid solution

Buffer pH

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Applications Notes

Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-1:2000; ELISA 1:20000; Not yet tested in other applications.