RSL3-4-Me
RSL3-4-Me is the active control of the target protein ligand Demethyl-RSL3 , which can be used for the synthesis of PROTAC.
Product Specifications
CAS Number
3049087-33-1
UNSPSC
12352005
Target
Ligands for Target Protein for PROTAC
Type
Reference compound
Related Pathways
PROTAC
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/rsl3-4-me.html
Smiles
O=C(OC)[C@@H]1N(C(CC)=O)[C@@H](C2=CC=C(C(O)=O)C=C2)C3=C(C(C=CC=C4)=C4N3)C1
Molecular Formula
C23H22N2O5
Molecular Weight
406.43
References & Citations
[1]Zheng C, et al. Structure-activity relationship study of RSL3-based GPX4 degraders and its potential noncovalent optimization. Eur J Med Chem. 2023 Jul 5;255:115393.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
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