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RSL3-4-Me

RSL3-4-Me is the active control of the target protein ligand Demethyl-RSL3 , which can be used for the synthesis of PROTAC.

Product Specifications

CAS Number

3049087-33-1

UNSPSC

12352005

Target

Ligands for Target Protein for PROTAC

Type

Reference compound

Related Pathways

PROTAC

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/rsl3-4-me.html

Smiles

O=C(OC)[C@@H]1N(C(CC)=O)[C@@H](C2=CC=C(C(O)=O)C=C2)C3=C(C(C=CC=C4)=C4N3)C1

Molecular Formula

C23H22N2O5

Molecular Weight

406.43

References & Citations

[1]Zheng C, et al. Structure-activity relationship study of RSL3-based GPX4 degraders and its potential noncovalent optimization. Eur J Med Chem. 2023 Jul 5;255:115393.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Frequently Asked Questions

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