XPA Polyclonal Antibody

Rabbit Anti-XPA Polyclonal Antibody

Product Specifications

Background

XPA encodes a zinc finger protein involved in DNA excision repair. The DNA repair protein complementing XP-A cells is part of the NER (nucleotide excision repair) complext which is responsible for repair of UV radiation-induced photoproducts and DNA adducts induced by chemical carcinogens. Mutations in this gene are associated with xeroderma pigmentosum complementation group A. Alternatively spliced transcript variants have been found for this gene.

CAS Number

9007-83-4

Product Name Alternative

XPA; XPAC; DNA repair protein complementing XP-A cells; Xeroderma pigmentosum group A-complementing protein

Gene ID

7507

Accession Number

P23025

Reactivity

Human, Mouse

Immunogen

Synthesized peptide derived from the C-terminal region of human XPA at AA range: 180-260

Clonality

Polyclonal

Tag

DNA repair protein complementing XP-A cells

Applications

WB, IHC, IF, ELISA

Purification Method

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration

1 mg/ml

Molecular Weight

40kD

Precautions

The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.

Shipping Conditions

Gel pack with blue ice.

Storage Conditions

Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Notes

XPA Polyclonal Antibody detects endogenous levels of XPA protein.

Observed Molecular Weight

Formulation

Liquid solution

Buffer pH

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Applications Notes

Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-1:2000; IHC 1:100-1:300; ELISA 1:10000; IF 1:50-200