UBR5 Polyclonal Antibody

Rabbit Anti-UBR5 Polyclonal Antibody

Product Specifications

Background

UBR5 encodes a progestin-induced protein, which belongs to the HECT (homology to E6-AP carboxyl terminus) family. The HECT family proteins function as E3 ubiquitin-protein ligases, targeting specific proteins for ubiquitin-mediated proteolysis. This gene is localized to chromosome 8q22 which is disrupted in a variety of cancers. This gene potentially has a role in regulation of cell proliferation or differentiation.

CAS Number

9007-83-4

Product Name Alternative

UBR5; EDD; EDD1; HYD; KIAA0896; E3 ubiquitin-protein ligase UBR5; E3 ubiquitin-protein ligase; HECT domain-containing 1; Hyperplastic discs protein homolog; hHYD; Progestin-induced protein

Gene ID

51366

Accession Number

O95071

Reactivity

Human, Mouse

Immunogen

Synthesized peptide derived from the N-terminal region of human UBR5 at AA range: 1-80

Clonality

Polyclonal

Tag

E3 ubiquitin-protein ligase UBR5

Applications

WB, IHC, IF, ELISA

Purification Method

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration

1 mg/ml

Molecular Weight

309kD

Precautions

The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.

Shipping Conditions

Gel pack with blue ice.

Storage Conditions

Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Notes

UBR5 Polyclonal Antibody detects endogenous levels of UBR5 protein.

Observed Molecular Weight

309

Formulation

Liquid solution

Buffer pH

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Applications Notes

Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-1:2000; IHC 1:100-1:300; ELISA 1:5000; IF 1:50-200

Other Product Names

UBR5; EDD; EDD1; HYD; KIAA0896; E3 ubiquitin-protein ligase UBR5; E3 ubiquitin-protein ligase; HECT domain-containing 1; Hyperplastic discs protein homolog; hHYD; Progestin-induced protein