Deoxyarbutin
Product Specifications
UNSPSC Description
Deoxyarbutin is an orally active tyrosinase inhibitor that can promote apoptosis of melanoma cells, enhance the vitality of mouse acinar cells, and has skin whitening and anti-tumor activity[1][2][3].
Target Antigen
Apoptosis; Tyrosinase
Type
Natural Products
Related Pathways
Apoptosis;Metabolic Enzyme/Protease
Applications
Metabolism-sugar/lipid metabolism
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/Deoxyarbutin.html
Purity
99.92
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
OC1=CC=C(OC2CCCCO2)C=C1
Molecular Weight
194.23
References & Citations
[1]Boissy RE, et al. DeoxyArbutin: a novel reversible tyrosinase inhibitor with effective in vivo skin lightening potency. Exp Dermatol. 2005 Aug;14(8):601-8. |[2]Ma L, et al. Deoxyarbutin displays antitumour activity against melanoma in vitro and in vivo through a p38-mediated mitochondria associated apoptotic pathway. Sci Rep. 2017 Aug 3;7(1):7197. |[3]Li Y, et al. Deoxyarbutin attenuates severe acute pancreatitis via the HtrA2/PGC-1α pathway. Free Radic Res. 2022 Sep-Oct;56(9-10):651-665.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-B1461/Deoxyarbutin-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-B1461/Deoxyarbutin-SDS-MedChemExpress.pdf
Clinical Information
No Development Reported
CAS Number
53936-56-4
Available Sizes
Curated Selection
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