Synphilin-1 Polyclonal Antibody

Rabbit Anti-Synphilin-1 Polyclonal Antibody

Product Specifications

Background

SNCAIP encodes Synphilin-1 containing several protein-protein interaction domains, including ankyrin-like repeats, a coiled-coil domain, and an ATP/GTP-binding motif. The synphilin-1 interacts with alpha-synuclein in neuronal tissue and may play a role in the formation of cytoplasmic inclusions and neurodegeneration. A mutation in this gene has been associated with Parkinson's disease. Alternative splicing results in multiple transcript variants.

CAS Number

9007-83-4

Product Name Alternative

SNCAIP; Synphilin-1; Sph1; Alpha-synuclein-interacting protein

Gene ID

9627

Accession Number

Q9Y6H5

Reactivity

Human, Mouse

Immunogen

Synthesized peptide derived from the C-terminal region of human Synphilin-1

Clonality

Polyclonal

Tag

Synphilin-1

Applications

WB, IHC, IF, ELISA

Purification Method

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration

1 mg/ml

Molecular Weight

100kD

Precautions

The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.

Shipping Conditions

Gel pack with blue ice.

Storage Conditions

Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Notes

Synphilin-1 Polyclonal Antibody detects endogenous levels of Synphilin-1 protein.

Observed Molecular Weight

100

Formulation

Liquid solution

Buffer pH

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Applications Notes

Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-1:2000; IHC 1:100-1:300; ELISA 1:10000; IF 1:50-200