RhoGEF p115 Polyclonal Antibody

Rabbit Anti-RhoGEF p115 Polyclonal Antibody

Product Specifications

Background

Rho GTPases play a fundamental role in numerous cellular processes that are initiated by extracellular stimuli that work through G protein coupled receptors. The rho guanine nucleotide exchange factor 1 may form complex with G proteins and stimulate Rho-dependent signals. Multiple alternatively spliced transcript variants have been found for this gene, but the full-length nature of some variants has not been defined.

CAS Number

9007-83-4

Product Name Alternative

ARHGEF1; Rho guanine nucleotide exchange factor 1; 115 kDa guanine nucleotide exchange factor; p115-RhoGEF; p115RhoGEF; Sub1.5

Gene ID

9138

Accession Number

Q92888

Reactivity

Human, Mouse, Rat

Immunogen

Synthesized peptide derived from the Internal region of human RhoGEF p115 at AA range: 140-220

Clonality

Polyclonal

Tag

Rho guanine nucleotide exchange factor 1

Applications

WB, ELISA, IHC

Purification Method

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration

1 mg/ml

Molecular Weight

105kD

Precautions

The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.

Shipping Conditions

Gel pack with blue ice.

Storage Conditions

Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Notes

RhoGEF p115 Polyclonal Antibody detects endogenous levels of RhoGEF p115 protein.

Observed Molecular Weight

105

Formulation

Liquid solution

Buffer pH

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Applications Notes

Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000; IHC 1:50-300; ELISA 1:2000-20000