Rab 3 GAP p150 Polyclonal Antibody

Rabbit Anti-Rab 3 GAP p150 Polyclonal Antibody

Product Specifications

Background

RAB3 GTPase activating non-catalytic protein subunit 2 encoded by RAB3GAP2 belongs to the RAB3 protein family, members of which are involved in regulated exocytosis of neurotransmitters and hormones. RAB3 GTPase activating non-catalytic protein subunit 2 forms the Rab3 GTPase-activating complex with RAB3GAP1, where it constitutes the regulatory subunit, whereas the latter functions as the catalytic subunit. RAB3GAP2 has the highest level of expression in the brain, consistent with it having a key role in neurodevelopment. Mutations in RAB3GAP2 are associated with Martsolf syndrome.

CAS Number

9007-83-4

Product Name Alternative

RAB3GAP2; KIAA0839; Rab3 GTPase-activating protein non-catalytic subunit; RGAP-iso; Rab3 GTPase-activating protein 150 kDa subunit; Rab3-GAP p150; Rab3-GAP150; Rab3-GAP regulatory subunit

Gene ID

25782

Accession Number

Q9H2M9

Reactivity

Human, Mouse, Rat, Monkey

Immunogen

Synthesized peptide derived from the Internal region of human Rab 3 GAP p150 at AA range: 390-470

Clonality

Polyclonal

Tag

Rab3 GTPase-activating protein non-catalytic subunit

Applications

WB, IHC, IF, ELISA

Purification Method

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration

1 mg/ml

Molecular Weight

156kD

Precautions

The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.

Shipping Conditions

Gel pack with blue ice.

Storage Conditions

Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Notes

Rab 3 GAP p150 Polyclonal Antibody detects endogenous levels of Rab 3 GAP p150 protein.

Observed Molecular Weight

156

Formulation

Liquid solution

Buffer pH

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Applications Notes

Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-1:2000; IHC 1:100-1:300; ELISA 1:40000; IF 1:50-200

Other Product Names

RAB3GAP2; KIAA0839; Rab3 GTPase-activating protein non-catalytic subunit; RGAP-iso; Rab3 GTPase-activating protein 150 kDa subunit; Rab3-GAP p150; Rab3-GAP150; Rab3-GAP regulatory subunit