Rab 3 GAP p130 Polyclonal Antibody

Rabbit Anti-Rab 3 GAP p130 Polyclonal Antibody

Product Specifications

Background

RAB3GAP1 encodes the catalytic subunit of a Rab GTPase activating protein. RAB3 GTPase activating protein catalytic subunit 1 forms a heterodimer with a non-catalytic subunit to specifically regulate the activity of members of the Rab3 subfamily of small G proteins. RAB3 GTPase activating protein catalytic subunit 1 mediates the hydrolysis of GTP bound Rab3 to the GDP bound form. Mutations in RAB3GAP1 are associated with Warburg micro syndrome. Alternate splicing results in multiple transcript variants.

CAS Number

9007-83-4

Product Name Alternative

RAB3GAP1; KIAA0066; RAB3GAP; Rab3 GTPase-activating protein catalytic subunit; RAB3 GTPase-activating protein 130 kDa subunit; Rab3-GAP p130; Rab3-GAP

Gene ID

22930

Accession Number

Q15042

Reactivity

Human, Rat, Mouse

Immunogen

Synthesized peptide derived from the Internal region of human Rab 3 GAP p130 at AA range: 510-590

Clonality

Polyclonal

Tag

Rab3 GTPase-activating protein catalytic subunit

Applications

WB, IHC, IF, ELISA

Purification Method

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration

1 mg/ml

Molecular Weight

117kD

Precautions

The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.

Shipping Conditions

Gel pack with blue ice.

Storage Conditions

Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Notes

Rab 3 GAP p130 Polyclonal Antibody detects endogenous levels of Rab 3 GAP p130 protein.

Observed Molecular Weight

117

Formulation

Liquid solution

Buffer pH

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Applications Notes

Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-1:2000; IHC 1:100-1:300; ELISA 1:40000; IF 1:50-200

Other Product Names

RAB3GAP1; KIAA0066; RAB3GAP; Rab3 GTPase-activating protein catalytic subunit; RAB3 GTPase-activating protein 130 kDa subunit; Rab3-GAP p130; Rab3-GAP