PMS1 Polyclonal Antibody

Rabbit Anti-PMS1 Polyclonal Antibody

Product Specifications

Background

PMS1 encodes a protein belonging to the DNA mismatch repair mutL/hexB family. PMS1 homolog 1, mismatch repair system component is thought to be involved in the repair of DNA mismatches, and it can form heterodimers with MLH1, a known DNA mismatch repair protein. Mutations in PMS1 cause hereditary nonpolyposis colorectal cancer type 3 (HNPCC3) either alone or in combination with mutations in other genes involved in the HNPCC phenotype, which is also known as Lynch syndrome.

CAS Number

9007-83-4

Product Name Alternative

PMS1; PMSL1; PMS1 protein homolog 1; DNA mismatch repair protein PMS1

Gene ID

5378

Accession Number

P54277

Reactivity

Human

Immunogen

Synthesized peptide derived from the Internal region of human PMS1 at AA range: 410-490

Clonality

Polyclonal

Tag

PMS1 protein homolog 1

Applications

WB, IHC, IF, ELISA

Purification Method

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration

1 mg/ml

Molecular Weight

105kD

Precautions

The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.

Shipping Conditions

Gel pack with blue ice.

Storage Conditions

Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Notes

PMS1 Polyclonal Antibody detects endogenous levels of PMS1 protein.

Observed Molecular Weight

105

Formulation

Liquid solution

Buffer pH

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Applications Notes

Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-1:2000; IHC 1:100-1:300; ELISA 1:10000; IF 1:50-200