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Tegafur-gimeracil-oteracil (potassium)

Tegafur-gimeracil-oteracil potassium (TS-1) is an oral anticancer agent composed of Tegafur , Gimeracil (HY-17469), and Oteracil potassium (HY-17511) at a molar ratio of 1:0.4:1. TS-1 can be utilized in research on the peritoneal dissemination of gastric cancer[1].

Product Specifications

CAS Number

150863-82-4

Product Name Alternative

S-1; TS-1

UNSPSC

12352005

Target

Nucleoside Antimetabolite/Analog; Xanthine Oxidase

Type

Reference compound

Related Pathways

Cell Cycle/DNA Damage; Metabolic Enzyme/Protease

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/tegafur-gimeracil-oteracil-potassium.html

Purity

99.96

Solubility

DMSO : < 1 mg/mL (ultrasonic; warming; heat to 60°C) |H2O : 5.56 mg/mL (ultrasonic)

Smiles

O=C(C1=NC(NC(N1)=O)=O)O[K].O=C2C=C(C(Cl)=CN2)O.O=C3NC(N(C4OCCC4)C=C3F)=O

Molecular Formula

C17H15ClFKN6O9

Molecular Weight

540.89

References & Citations

[1]Osugi H, et al. Oral fluoropyrimidine anticancer drug TS-1 for gastric cancer patients with peritoneal dissemination. Oncol Rep. 2002 Jul-Aug;9 (4) :811-5.

Shipping Conditions

Room Temperature

Storage Conditions

4°C (Powder, sealed storage, away from moisture)

Scientific Category

Reference compound1

Clinical Information

Phase 4

Available Sizes

Frequently Asked Questions

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