PD117588
PD117588 is a quinolone antibacterial agent with a broad range of antibacterial activity. PD117588 exhibits excellent activity against a variety of Gram-positive and Gram-negative bacteria from cancer patients, especially against all Gram-positive strains, including methicillin-resistant Staphylococcus aureus, coagulase-negative Staphylococci, and Enterococci. PD117588 is also very effective against most Gram-negative bacilli, although ciprofloxacin shows stronger activity against Pseudomonas aeruginosa. Compared with other quinolone antibiotics, the minimum inhibitory concentration of PD117588 outperforms most of the tested microorganisms, including imipenem and ceftazidime[1].
Product Specifications
CAS Number
[99734-97-1]
UNSPSC
12352005
Target
Antibiotic
Type
Reference compound
Related Pathways
Anti-infection
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/pd117588.html
Smiles
O=C(C1=CN(C2CC2)C3=C(C(N4CCC(C4)CNCC)=C(C=C3C1=O)F)F)O
Molecular Formula
C20H23F2N3O3
Molecular Weight
391.41
References & Citations
[1]In-vitro activity of PD 117558, a new quinolone against bacterial isolates from cancer patients
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
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