Welcome to GenPrice! Check out our latest updates.

Shopping Cart (0)

Your cart is empty

Add some products to get started!

P15 Polyclonal Antibody

Rabbit Anti-p15 Polyclonal Antibody

Product Specifications

Background

CDKN2B lies adjacent to the tumor suppressor gene CDKN2A in a region that is frequently mutated and deleted in a wide variety of tumors. CDKN2B encodes a cyclin-dependent kinase inhibitor, which forms a complex with CDK4 or CDK6, and prevents the activation of the CDK kinases, thus cyclin dependent kinase inhibitor 2B functions as a cell growth regulator that controls cell cycle G1 progression. The expression of CDKN2B was found to be dramatically induced by TGF beta, which suggested its role in the TGF beta induced growth inhibition. Two alternatively spliced transcript variants of CDKN2B, which encode distinct proteins, have been reported.

CAS Number

9007-83-4

Product Name Alternative

CDKN2B; MTS2; Cyclin-dependent kinase 4 inhibitor B; Multiple tumor suppressor 2; MTS-2; p14-INK4b; p15-INK4b; p15INK4B

Gene ID

1030

Accession Number

P42772

Reactivity

Human, Mouse, Rat

Immunogen

Synthesized peptide derived from the C-terminal region of human p15 at AA range: 60-140

Clonality

Polyclonal

Tag

Cyclin-dependent kinase 4 inhibitor B

Applications

WB, IHC, IF, ELISA

Purification Method

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration

1 mg/ml

Molecular Weight

14kD

Precautions

The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.

Shipping Conditions

Gel pack with blue ice.

Storage Conditions

Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Notes

P15 Polyclonal Antibody detects endogenous levels of p15 protein.

Product Datasheet

https://www.abbkine.com/datasheet/ABP52098.pdf

Observed Molecular Weight

14

Formulation

Liquid solution

Buffer pH

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Applications Notes

Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-1:2000; IHC 1:100-1:300; IF 1:200-1:1000; ELISA 1:40000; Not yet tested in other applications.

Other Product Names

CDKN2B; MTS2; Cyclin-dependent kinase 4 inhibitor B; Multiple tumor suppressor 2; MTS-2; p14-INK4b; p15-INK4b; p15INK4B

Tested Applications

WB, IHC, IF, IP, ELISA

Host or Source

Rabbit

Accession Number URL

http://www.uniprot.org/uniprot/P42772

Isotype

Rabbit IgG

Available Sizes

Curated Selection

Explore Other Products

Discover premium biology products from our extensive collection of 20M+ items

COPS8 Polyclonal Antibody, HRP Conjugated
bs-9119R-HRP 100 µL

COPS8 Polyclonal Antibody, HRP Conjugated

Ask
View Details
Human GDF1 qPCR Primer Pair
QH14841S 200 Tests

Human GDF1 qPCR Primer Pair

Ask
View Details
Stromelysin-1 (MMP3) Antibody
abx170380-01 100 µL

Stromelysin-1 (MMP3) Antibody

Ask
View Details
Stromelysin-1 (MMP3) Antibody
abx170380-02 200 µL

Stromelysin-1 (MMP3) Antibody

Ask
View Details
Stromelysin-1 (MMP3) Antibody
abx170380-03 1 mL

Stromelysin-1 (MMP3) Antibody

Ask
View Details
DMRTC2 Antibody
DF10062-01 100 µL

DMRTC2 Antibody

Ask
View Details