Nrf3 Polyclonal Antibody

Rabbit Anti-Nrf3 Polyclonal Antibody

Product Specifications

Background

NFE2L3 encodes a member of the cap ‘n' collar basic-region leucine zipper family of transcription factors. Nuclear factor, erythroid 2 like 3 heterodimerizes with small musculoaponeurotic fibrosarcoma factors to bind antioxidant response elements in target genes. Nuclear factor, erythroid 2 like 3 is a membrane bound glycoprotein that is targeted to the endoplasmic reticulum and the nuclear envelope. Pseudogenes of NFE2L3 are found on chromosomes 16, 17, and 18.

CAS Number

9007-83-4

Product Name Alternative

NFE2L3; NRF3; Nuclear factor erythroid 2-related factor 3; NF-E2-related factor 3; NFE2-related factor 3; Nuclear factor; erythroid derived 2, like 3

Gene ID

9603

Accession Number

Q9Y4A8

Reactivity

Human, Mouse

Immunogen

Synthesized peptide derived from the Internal region of human Nrf3 at AA range: 460-540

Clonality

Polyclonal

Tag

Nuclear factor erythroid 2-related factor 3

Applications

WB, ELISA

Purification Method

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration

1 mg/ml

Molecular Weight

75kD

Precautions

The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.

Shipping Conditions

Gel pack with blue ice.

Storage Conditions

Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Notes

Nrf3 Polyclonal Antibody detects endogenous levels of Nrf3 protein.

Observed Molecular Weight

Formulation

Liquid solution

Buffer pH

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Applications Notes

Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-1:2000; ELISA 1:10000; Not yet tested in other applications.