Sodium diatrizoate

Sodium diatrizoate (Diatrizoic acid sodium salt) is an iodinated radiocontrast agent and has the potential for radiographic imaging of the airways. Sodium diatrizoate induces mitochondrial turnover and oxidative stress, and activating apoptosis by dysregulating calcium[1][2].

Product Specifications

CAS Number

[737-31-5]

Product Name Alternative

Diatrizoic acid (sodium salt) ; Sodium amidotrizoate

UNSPSC

12352005

Hazard Statement

H317, H334

Target

Apoptosis

Type

Reference compound

Related Pathways

Apoptosis

Field of Research

Inflammation/Immunology

Assay Protocol

https://www.medchemexpress.com/Sodium_diatrizoate.html

Purity

99.50

Solubility

DMSO : 100 mg/mL (ultrasonic) |H2O : ≥ 50 mg/mL

Smiles

O=C(O[Na])C1=C(I)C(NC(C)=O)=C(I)C(NC(C)=O)=C1I

Molecular Formula

C11H8I3N2NaO4

Molecular Weight

635.90

Precautions

H317, H334

References & Citations

[1]El-Gendy N, et al. Dry powdered aerosols of diatrizoic acid nanoparticle agglomerates as a lung contrast agent. Int J Pharm. 2010 May 31;391 (1-2) :305-12.|[2]Dakota B Ward, et al. Radiocontrast Agent Diatrizoic Acid Induces Mitophagy and Oxidative Stress via Calcium Dysregulation. Int J Mol Sci. 2019 Aug 21;20 (17) :4074.