NBPF1/9/10/12/14/15/16/20 Polyclonal Antibody

Rabbit Anti-NBPF1/9/10/12/14/15/16/20 Polyclonal Antibody

Product Specifications

Background

NBPF1 is a member of the neuroblastoma breakpoint family (NBPF) which consists of dozens of recently duplicated genes primarily located in segmental duplications on human chromosome 1. This gene family has experienced its greatest expansion within the human lineage and has expanded, to a lesser extent, among primates in general. Members of this gene family are characterized by tandemly repeated copies of DUF1220 protein domains. Gene copy number variations in the human chromosomal region 1q21. , where most DUF1220 domains are located, have been implicated in a number of developmental and neurogenetic diseases such as microcephaly, macrocephaly, autism, schizophrenia, mental retardation, congenital heart disease, neuroblastoma, and congenital kidney and urinary tract anomalies. Altered expression of some gene family members is associated with several types of cancer. This gene family contains numerous pseudogenes.

CAS Number

9007-83-4

Product Name Alternative

NBPF12; COAS1; KIAA1245; Neuroblastoma breakpoint family member 12; Chromosome 1 amplified sequence 1; NBPF10; Neuroblastoma breakpoint family member 10; NBPF16; Neuroblastoma breakpoint family member 16; NBPF1; KIAA1693; Neuroblastoma brea

Gene ID

55672/400818/284565/25832

Accession Number

Q5TAG4/Q6P3W6/Q5SXJ2/Q3BBV0/Q3BBW0/Q3BBV1/Q8N660/Q5TI25

Reactivity

Human

Immunogen

Synthesized peptide derived from the C-terminal region of human NBPF1/9/10/12/14/15/16/20 at AA range: 700-780

Clonality

Polyclonal

Tag

Neuroblastoma breakpoint family member 12

Applications

WB, IHC, IF, ELISA

Purification Method

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration

1 mg/ml

Molecular Weight

36kD

Precautions

The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.

Shipping Conditions

Gel pack with blue ice.

Storage Conditions

Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Notes

NBPF1/9/10/12/14/15/16/20 Polyclonal Antibody detects endogenous levels of NBPF1/9/10/12/14/15/16/20 protein.

Observed Molecular Weight

Formulation

Liquid solution

Buffer pH

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Applications Notes

Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-1:2000; IHC 1:100-1:300; ELISA 1:40000; IF 1:50-200