MEL-1B-R Polyclonal Antibody

Rabbit Anti-MEL-1B-R Polyclonal Antibody

Product Specifications

Background

MTNR1B encodes one of two high affinity forms of a receptor for melatonin, the primary hormone secreted by the pineal gland. Melatonin receptor type 1B is an integral membrane protein that is a G-protein coupled, 7-transmembrane receptor. It is found primarily in the retina and brain although this detection requires RT-PCR. It is thought to participate in light-dependent functions in the retina and may be involved in the neurobiological effects of melatonin.

CAS Number

9007-83-4

Product Name Alternative

MTNR1B; Melatonin receptor type 1B; Mel-1B-R; Mel1b receptor

Gene ID

4544

Accession Number

P49286

Reactivity

Human

Immunogen

Synthesized peptide derived from the C-terminal region of human MEL-1B-R at AA range: 270-350

Clonality

Polyclonal

Tag

Melatonin receptor type 1B

Applications

WB, IHC

Purification Method

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration

1 mg/ml

Molecular Weight

40kD

Precautions

The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.

Shipping Conditions

Gel pack with blue ice.

Storage Conditions

Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Notes

MEL-1B-R Polyclonal Antibody detects endogenous levels of MEL-1B-R protein.

Observed Molecular Weight

Formulation

Liquid solution

Buffer pH

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Applications Notes

Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000; IHC 1:50-300