What is the catalog number for Kv1.3 Polyclonal Antibody?

The catalog number for Kv1.3 Polyclonal Antibody is ABP51688.

What sizes are available for Kv1.3 Polyclonal Antibody?

Kv1.3 Polyclonal Antibody is available in the following size(s): 30 µL, 100 µL, 200 µL.

How many pack sizes does Kv1.3 Polyclonal Antibody come in?

Kv1.3 Polyclonal Antibody is available in 3 different pack sizes.

Is Kv1.3 Polyclonal Antibody in stock?

Kv1.3 Polyclonal Antibody is currently made to order / not held in immediate stock. Contact us for lead time.

What is the recommended positive control for this assay?

A recommended positive control, where one is specified by the manufacturer, is listed on the datasheet or in the assay protocol.

How should this product be stored?

Storage conditions depend on the specific reagent and are listed on the product datasheet, with most antibodies and proteins requiring -20°C unless stated otherwise. It is your responsibility to store the product correctly immediately upon receipt; damage from improper storage after delivery is not eligible for replacement.

Is this product animal-origin-free?

Animal-origin-free status, where applicable, is noted on the datasheet under formulation details.

Kv1.3 Polyclonal Antibody

Rabbit Anti-Kv1.3 Polyclonal Antibody

Product Specifications

Background

Potassium channels represent the most complex class of voltage-gated ion channels from both functional and structural standpoints. Their diverse functions include regulating neurotransmitter release, heart rate, insulin secretion, neuronal excitability, epithelial electrolyte transport, smooth muscle contraction, and cell volume. Four sequence-related potassium channel genes - shaker, shaw, shab, and shal - have been identified in Drosophila, and each has been shown to have human homolog (s) . KCNA3 encodes a member of the potassium channel, voltage-gated, shaker-related subfamily. Potassium voltage-gated channel subfamily A member 3 contains six membrane-spanning domains with a shaker-type repeat in the fourth segment. It belongs to the delayed rectifier class, members of which allow nerve cells to efficiently repolarize following an action potential. It plays an essential role in T-cell proliferation and activation. This gene appears to be intronless and it is clustered together with KCNA2 and KCNA10 genes on chromosome 1.

CAS Number

9007-83-4

Product Name Alternative

KCNA3; HGK5; Potassium voltage-gated channel subfamily A member 3; HGK5; HLK3; HPCN3; Voltage-gated K (+) channel HuKIII; Voltage-gated potassium channel subunit Kv1.3

Gene ID

3738

Accession Number

P22001

Reactivity

Human, Mouse, Rat

Immunogen

Synthesized peptide derived from human Kv1.3 around the non-phosphorylation site of Y187

Clonality

Polyclonal

Tag

Potassium voltage-gated channel subfamily A member 3

Applications

WB, IHC, IF, ELISA

Purification Method

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration

1 mg/ml

Precautions

The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.

Shipping Conditions

Gel pack with blue ice.

Storage Conditions

Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Notes

Kv1.3 Polyclonal Antibody detects endogenous levels of Kv1.3 protein.

Formulation

Liquid solution

Buffer pH

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Applications Notes

Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-1:2000; IHC 1:100-1:300; IF 1:200-1:1000; ELISA 1:20000; Not yet tested in other applications.

Other Product Names

KCNA3; HGK5; Potassium voltage-gated channel subfamily A member 3; HGK5; HLK3; HPCN3; Voltage-gated K (+) channel HuKIII; Voltage-gated potassium channel subunit Kv1.3