IQGAP1 Polyclonal Antibody

Rabbit Anti-IQGAP1 Polyclonal Antibody

Product Specifications

Background

IQGAP1 encodes a member of the IQGAP family. Ras GTPase-activating-like protein IQGAP1 contains four IQ domains, one calponin homology domain, one Ras-GAP domain and one WW domain. It interacts with components of the cytoskeleton, with cell adhesion molecules, and with several signaling molecules to regulate cell morphology and motility. Expression of the protein is upregulated by gene amplification in two gastric cancer cell lines.

CAS Number

9007-83-4

Product Name Alternative

IQGAP1; KIAA0051; Ras GTPase-activating-like protein IQGAP1; p195

Gene ID

8826

Accession Number

P46940

Reactivity

Human, Mouse

Immunogen

Synthesized peptide derived from the N-terminal region of human IQGAP1 at AA range: 220-300

Clonality

Polyclonal

Tag

Ras GTPase-activating-like protein IQGAP1

Applications

WB, IHC

Purification Method

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration

1 mg/ml

Molecular Weight

190kD

Precautions

The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.

Shipping Conditions

Gel pack with blue ice.

Storage Conditions

Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Notes

IQGAP1 Polyclonal Antibody detects endogenous levels of IQGAP1 protein.

Observed Molecular Weight

190

Formulation

Liquid solution

Buffer pH

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Applications Notes

Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000; IHC 1:50-300