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HMG-2 Polyclonal Antibody

Rabbit Anti-HMG-2 Polyclonal Antibody

Product Specifications

Background

HMGB2 encodes a member of the non-histone chromosomal high mobility group protein family. The proteins of this family are chromatin-associated and ubiquitously distributed in the nucleus of higher eukaryotic cells. In vitro studies have demonstrated that high mobility group protein B2 is able to efficiently bend DNA and form DNA circles. These studies suggest a role in facilitating cooperative interactions between cis-acting proteins by promoting DNA flexibility. This protein was also reported to be involved in the final ligation step in DNA end-joining processes of DNA double-strand breaks repair and V (D) J recombination.

Product Name Alternative

HMGB2; HMG2; High mobility group protein B2; High mobility group protein 2; HMG-2

Gene ID

3148

Accession Number

P26583

Reactivity

Human, Mouse, Rat

Immunogen

Synthesized peptide derived from the Internal region of human HMG-2 at AA range: 100-180

Clonality

Polyclonal

Tag

High mobility group protein B2

Applications

WB, IHC, IF, ELISA

Purification Method

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration

1 mg/ml

Molecular Weight

27kD

Precautions

The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.

Shipping Conditions

Gel pack with blue ice.

Storage Conditions

Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Notes

HMG-2 Polyclonal Antibody detects endogenous levels of HMG-2 protein.

Product Datasheet

https://www.abbkine.com/datasheet/ABP51541.pdf

Observed Molecular Weight

27

Formulation

Liquid solution

Buffer pH

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Applications Notes

Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-1:2000; IHC 1:100-1:300; IF 1:200-1:1000; ELISA 1:10000; Not yet tested in other applications.

Other Product Names

HMGB2; HMG2; High mobility group protein B2; High mobility group protein 2; HMG-2

Tested Applications

WB, IHC, IF, IP, ELISA

Host or Source

Rabbit

Accession Number URL

http://www.uniprot.org/uniprot/P26583

CAS Number

9007-83-4

Isotype

Rabbit IgG

Available Sizes

Curated Selection

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