Oxolinic acid (Standard)
Product Specifications
UNSPSC Description
Oxolinic acid (Standard) is the analytical standard of Oxolinic acid. This product is intended for research and analytical applications. Oxolinic acid is an antibiotic against both Gram-negative and Gram-positive bacteria. Oxolinic acid can be used for the research of acute and chronic urinary tract infections. Oxolinic acid is a DNA/RNA synthesis inhibitor. Oxolinic acid acts a dopamine uptake inhibitor and stimulants locomotor effect in mice[1][2][3].
Target Antigen
Antibiotic; Bacterial; DNA/RNA Synthesis
Type
Reference Standards
Related Pathways
Anti-infection;Cell Cycle/DNA Damage
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/oxolinic-acid-standard.html
Purity
97.08
Solubility
H2O : < 0.1 mg/mL
Smiles
O=C(C1=CN(CC)C2=C(C=C3C(OCO3)=C2)C1=O)O
Molecular Weight
261.23
References & Citations
[1]M J Kershaw, et al. The antibacterial and pharmacological activity of oxolinic acid (Prodoxol). J Antimicrob Chemother. 1975 Sep;1(3):311-5.|[2]S H Manes, et al. Inhibition of RNA synthesis by oxolinic acid is unrelated to average DNA supercoiling. J Bacteriol. 1983 Jul; 155(1): 420-423.|[3]J Garcia de Mateos-Verchere, et al. Behavioural and neurochemical evidence that the antimicrobial agent oxolinic acid is a dopamine uptake inhibitor. Eur Neuropsychopharmacol. 1998 Dec;8(4):255-9.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, sealed storage, away from moisture and light)
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-B1002R/Oxolinic-acid-Standard-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-B1002R/
Clinical Information
No Development Reported
CAS Number
14698-29-4
Available Sizes
Curated Selection
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