HDAC7 Polyclonal Antibody

Rabbit Anti-HDAC7 Polyclonal Antibody

Product Specifications

Background

Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. Histone deacetylase 7 encoded by HDAC7 has sequence homology to members of the histone deacetylase family. HDAC7 is orthologous to mouse HDAC7 gene whose protein promotes repression mediated via the transcriptional corepressor SMRT. Alternatively spliced transcript variants encoding different isoforms have been found for HDAC7.

CAS Number

9007-83-4

Product Name Alternative

HDAC7; HDAC7A; Histone deacetylase 7; HD7; Histone deacetylase 7A; HD7a

Gene ID

51564

Accession Number

Q8WUI4

Reactivity

Human, Mouse, Rat

Immunogen

Synthesized peptide derived from human HDAC7 around the non-phosphorylation site of S155

Clonality

Polyclonal

Tag

Histone deacetylase 7

Applications

WB, ELISA

Purification Method

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration

1 mg/ml

Molecular Weight

103kD

Precautions

The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.

Shipping Conditions

Gel pack with blue ice.

Storage Conditions

Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Notes

HDAC7 Polyclonal Antibody detects endogenous levels of HDAC7 protein.

Observed Molecular Weight

103

Formulation

Liquid solution

Buffer pH

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Applications Notes

Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-1:2000; ELISA 1:10000; Not yet tested in other applications.