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GM2/GD2 synthase Polyclonal Antibody

Rabbit Anti-GM2/GD2 synthase Polyclonal Antibody

Product Specifications

Background

GM2 and GD2 gangliosides are sialic acid-containing glycosphingolipids. Beta-1,4 N-acetylgalactosaminyltransferase 1 is the enzyme involved in the biosynthesis of G (M2) and G (D2) glycosphingolipids. Beta-1,4 N-acetylgalactosaminyltransferase 1 catalyzes the transfer of GalNAc into G (M3) and G (D3) by a beta-1,4 linkage, resulting in the synthesis of G (M2) and G (D2), respectively. Three transcript variants encoding different isoforms have been found for this gene.

Product Name Alternative

B4GALNT1; GALGT; SIAT2; Beta-1; 4 N-acetylgalactosaminyltransferase 1; (N-acetylneuraminyl) -galactosylglucosylceramide; GM2/GD2 synthase; GalNAc-T

Gene ID

2583

Accession Number

Q00973

Reactivity

Human, Mouse, Rat

Immunogen

Synthesized peptide derived from the Internal region of human GM2/GD2 synthase at AA range: 250-330

Clonality

Polyclonal

Tag

Beta-1,4 N-acetylgalactosaminyltransferase 1

Applications

WB, ELISA

Purification Method

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration

1 mg/ml

Molecular Weight

60kD

Precautions

The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.

Shipping Conditions

Gel pack with blue ice.

Storage Conditions

Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Notes

GM2/GD2 synthase Polyclonal Antibody detects endogenous levels of GM2/GD2 synthase protein.

Product Datasheet

https://www.abbkine.com/datasheet/ABP51441.pdf

Observed Molecular Weight

60

Formulation

Liquid solution

Buffer pH

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Applications Notes

Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-1:2000; ELISA 1:5000; Not yet tested in other applications.

Other Product Names

B4GALNT1; GALGT; SIAT2; Beta-1; 4 N-acetylgalactosaminyltransferase 1; (N-acetylneuraminyl) -galactosylglucosylceramide; GM2/GD2 synthase; GalNAc-T

Tested Applications

WB, IHC, IF, IP, ELISA

Host or Source

Rabbit

Accession Number URL

http://www.uniprot.org/uniprot/Q00973

CAS Number

9007-83-4

Isotype

Rabbit IgG

Available Sizes

Curated Selection

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