GCP4 Polyclonal Antibody

Rabbit Anti-GCP4 Polyclonal Antibody

Product Specifications

Background

TUBGCP4 encodes a component of the gamma-tubulin ring complex, gamma-tubulin complex component 4, which is required for microtubule nucleation. In mammalian cells, the protein localizes to centrosomes in association with gamma-tubulin. Crystal structure analysis revealed a structure composed of five helical bundles arranged around conserved hydrophobic cores. An exposed surface area located in the C-terminal domain is essential and sufficient for direct binding to gamma-tubulin. Mutations in this gene that alter microtubule organization are associated with microcephaly and chorioretinopathy. Alternative splicing results in multiple transcript variants.

CAS Number

9007-83-4

Product Name Alternative

TUBGCP4; 76P; GCP4; Gamma-tubulin complex component 4; GCP-4; hGCP4; Gamma-ring complex protein 76 kDa; h76p; hGrip76

Gene ID

27229

Accession Number

Q9UGJ1

Reactivity

Human, Mouse

Immunogen

Synthesized peptide derived from the Internal region of human GCP4 at AA range: 160-240

Clonality

Polyclonal

Tag

Gamma-tubulin complex component 4

Applications

WB, IHC, IF, ELISA

Purification Method

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration

1 mg/ml

Molecular Weight

76kD

Precautions

The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.

Shipping Conditions

Gel pack with blue ice.

Storage Conditions

Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Notes

GCP4 Polyclonal Antibody detects endogenous levels of GCP4 protein.

Observed Molecular Weight

Formulation

Liquid solution

Buffer pH

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Applications Notes

Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-1:2000; IHC 1:100-1:300; ELISA 1:10000; IF 1:50-200