GAP1-InsP4 BP Polyclonal Antibody

Rabbit Anti-GAP1-InsP4 BP Polyclonal Antibody

Product Specifications

Background

RASA3 encodes a protein that binds inositol 1,3,4,5-tetrakisphosphate and stimulates the GTPase activity of Ras p21. Ras GTPase-activating protein 3 functions as a negative regulator of the Ras signalling pathway. It is localized to the cell membrane via a pleckstrin homology (PH) domain in the C-terminal region. Alternative splicing results in multiple transcript variants.

CAS Number

9007-83-4

Product Name Alternative

RASA3; Ras GTPase-activating protein 3; GAP1 (IP4BP) ; Ins P4-binding protein

Gene ID

22821

Accession Number

Q14644

Reactivity

Human, Mouse, Rat

Immunogen

Synthesized peptide derived from the Internal region of human GAP1-InsP4 BP at AA range: 220-300

Clonality

Polyclonal

Tag

Ras GTPase-activating protein 3

Applications

WB, ELISA

Purification Method

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration

1 mg/ml

Molecular Weight

95kD

Precautions

The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.

Shipping Conditions

Gel pack with blue ice.

Storage Conditions

Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Notes

GAP1-InsP4 BP Polyclonal Antibody detects endogenous levels of GAP1-InsP4 BP protein.

Observed Molecular Weight

Formulation

Liquid solution

Buffer pH

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Applications Notes

Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-1:2000; ELISA 1:40000; Not yet tested in other applications.