GABAA Rα6 Polyclonal Antibody

Rabbit Anti-GABAA Rα6 Polyclonal Antibody

Product Specifications

Background

GABA is the major inhibitory neurotransmitter in the mammalian brain where it acts at GABA-A receptors, which are ligand-gated chloride channels. Chloride conductance of these channels can be modulated by agents such as benzodiazepines that bind to the GABA-A receptor. At least 16 distinct subunits of GABA-A receptors have been identified.

CAS Number

9007-83-4

Product Name Alternative

GABRA6; Gamma-aminobutyric acid receptor subunit alpha-6; GABA (A) receptor subunit alpha-6

Gene ID

2559

Accession Number

Q16445

Reactivity

Human, Mouse, Rat

Immunogen

Synthesized peptide derived from the Internal region of human GABAA rangle: Rα6 at AA range: 30-110

Clonality

Polyclonal

Tag

Gamma-aminobutyric acid receptor subunit alpha-6

Applications

WB, ELISA

Purification Method

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration

1 mg/ml

Molecular Weight

51kD

Precautions

The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.

Shipping Conditions

Gel pack with blue ice.

Storage Conditions

Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Notes

GABAA Rα6 Polyclonal Antibody detects endogenous levels of GABAA Rα6 protein.

Observed Molecular Weight

Formulation

Liquid solution

Buffer pH

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Applications Notes

Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-1:2000; ELISA 1:40000; Not yet tested in other applications.