Frizzled-3 Polyclonal Antibody

Rabbit Anti-Frizzled-3 Polyclonal Antibody

Product Specifications

Background

FZD3 is a member of the frizzled gene family. Members of this family encode seven-transmembrane domain proteins that are receptors for the wingless type MMTV integration site family of signaling proteins. Most frizzled receptors are coupled to the beta-catenin canonical signaling pathway. The function of Frizzled-3 is unknown, although it may play a role in mammalian hair follicle development. Alternative splicing results in multiple transcript variants. FZD3 is a susceptibility locus for schizophrenia.

CAS Number

9007-83-4

Product Name Alternative

FZD3; Frizzled-3; Fz-3; hFz3

Gene ID

7976

Accession Number

Q9NPG1

Reactivity

Human, Mouse

Immunogen

Synthesized peptide derived from the Internal region of human Frizzled-3 at AA range: 110-190

Clonality

Polyclonal

Tag

Frizzled-3

Applications

WB, IF, ELISA

Purification Method

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration

1 mg/ml

Molecular Weight

76kD

Precautions

The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.

Shipping Conditions

Gel pack with blue ice.

Storage Conditions

Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Notes

Frizzled-3 Polyclonal Antibody detects endogenous levels of Frizzled-3 protein.

Observed Molecular Weight

Formulation

Liquid solution

Buffer pH

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Applications Notes

Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-1:2000; IF 1:200-1:1000; ELISA 1:10000; Not yet tested in other applications.