Ezrin Polyclonal Antibody
Rabbit Anti-Ezrin Polyclonal Antibody
Product Specifications
Background
The cytoplasmic peripheral membrane protein encoded by EZR functions as a protein-tyrosine kinase substrate in microvilli. As a member of the ERM protein family, this protein serves as an intermediate between the plasma membrane and the actin cytoskeleton. This protein plays a key role in cell surface structure adhesion, migration and organization, and it has been implicated in various human cancers. A pseudogene located on chromosome 3 has been identified for EZR. Alternatively spliced variants have also been described for EZR.
CAS Number
9007-83-4
Product Name Alternative
EZR; VIL2; Ezrin; Cytovillin; Villin-2; p81
Gene ID
7430
Accession Number
P15311
Reactivity
Human, Mouse, Rat
Immunogen
Synthesized peptide derived from the C-terminal region of human Ezrin at AA range: 480-560
Clonality
Polyclonal
Tag
Ezrin
Applications
WB, IF, ELISA
Purification Method
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration
1 mg/ml
Molecular Weight
70kD
Precautions
The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.
Shipping Conditions
Gel pack with blue ice.
Storage Conditions
Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
Notes
Ezrin Polyclonal Antibody detects endogenous levels of Ezrin protein.
Observed Molecular Weight
70
Formulation
Liquid solution
Buffer pH
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Applications Notes
Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-1:2000; ELISA 1:20000; IF 1:50-200
Other Product Names
EZR; VIL2; Ezrin; Cytovillin; Villin-2; p81
Tested Applications
WB, IHC, IF, IP, ELISA
Host or Source
Rabbit
Accession Number URL
http://www.uniprot.org/uniprot/P15311
Isotype
Rabbit IgG
Available Sizes
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