MB05032
Product Specifications
UNSPSC Description
MB05032 is a special and efficacious gluconeogenesis inhibitor targeted the AMP binding site of fructose 1,6-bisphosphatase (FBPase) with an IC50 value of 16 nM.
Target Antigen
FBPase
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
Metabolism-sugar/lipid metabolism
Field of Research
Metabolic Disease
Assay Protocol
https://www.medchemexpress.com/mb05032.html
Solubility
DMSO : 50 mg/mL (ultrasonic)
Smiles
CC(C)CC1=C(C2=CC=C(P(O)(O)=O)O2)N=C(N)S1
Molecular Weight
302.29
References & Citations
[1]Erion MD, et al. MB06322 (CS-917): A potent and selective inhibitor of fructose 1,6-bisphosphatase for controlling gluconeogenesis in type 2 diabetes. Proc Natl Acad Sci U S A. 2005 May 31;102(22):7970-5.|[2]Zhang Y, et al. Fructose-1,6-bisphosphatase regulates glucose-stimulated insulin secretion of mouse pancreatic beta-cells. Endocrinology. 2010 Oct;151(10):4688-95.
Shipping Conditions
Room Temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-16307/MB05032-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-16307/MB05032-SDS-MedChemExpress.pdf
Clinical Information
No Development Reported
CAS Number
261365-11-1
Available Sizes
Curated Selection
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
201-12-0278 96 Tests
Human cytotoxic T lymphocyte associated antigen 4 (CTLA-4) ELISA Kit
Ask
View Details 