Picloxydine

Picloxydine is a heterocyclic biguanide with antibacterial and antiplaque activity.

Product Specifications

CAS Number

[5636-92-0]

UNSPSC

12352005

Hazard Statement

H302-H315-H319-H335

Target

Bacterial

Type

Reference compound

Related Pathways

Anti-infection

Applications

COVID-19-immunoregulation

Field of Research

Infection

Assay Protocol

https://www.medchemexpress.com/Picloxydine.html

Purity

98.99

Solubility

DMSO : 11.36 mg/mL (ultrasonic; warming; adjust pH to 5 with HCl; heat to 60°C)

Smiles

N=C(N1CCN(C(NC(NC2=CC=C(Cl)C=C2)=N)=N)CC1)NC(NC3=CC=C(Cl)C=C3)=N

Molecular Formula

C20H24Cl2N10

Molecular Weight

475.38

Precautions

P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

References & Citations

[1]Newcomb GM, et al. An in vivo comparison of chlorhexidine and picloxydine mouthrinses: a possible association between chemical structure and antiplaque activity. J Periodontol. 1977 May;48 (5) :282-4.|[2]Obikili AG, et al. A double-blind comparison of picloxydine dihydrochloride (Vitabact eye drops) and sulfacetamide eye drops in the topical therapy of trachoma. Rev Int Trach Pathol Ocul Trop Subtrop Sante Publique. 1988;65 (3-4) :119-32.