C1q-B Polyclonal Antibody

Rabbit Anti-C1q-B Polyclonal Antibody

Product Specifications

Background

C1QB encodes a major constituent of the human complement subcomponent C1q. C1q associates with C1r and C1s in order to yield the first component of the serum complement system. Deficiency of C1q has been associated with lupus erythematosus and glomerulonephritis. C1q is composed of 18 polypeptide chains: six A-chains, six B-chains, and six C-chains. Each chain contains a collagen-like region located near the N terminus and a C-terminal globular region. The A-, B-, and C-chains are arranged in the order A-C-B on chromosome 1. This gene encodes the B-chain polypeptide of human complement subcomponent C1q.

CAS Number

9007-83-4

Product Name Alternative

C1QB; Complement C1q subcomponent subunit B

Gene ID

713

Accession Number

P02746

Reactivity

Human, Rat, Mouse

Immunogen

Synthesized peptide derived from the C-terminal region of human C1q-B at AA range: 130-210

Clonality

Polyclonal

Tag

Complement C1q subcomponent subunit B

Applications

WB, Flow Cyt, IHC, IF, ELISA

Purification Method

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration

1 mg/ml

Molecular Weight

28kD

Precautions

The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.

Shipping Conditions

Gel pack with blue ice.

Storage Conditions

Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Notes

C1q-B Polyclonal Antibody detects endogenous levels of C1q-B protein.

Observed Molecular Weight

Formulation

Liquid solution

Buffer pH

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Applications Notes

Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000; Flow Cyt 1:50-200; IHC 1:100-500; IF/ICC1:100-500; ELISA 1:5000-20000