BRMS-1 Polyclonal Antibody

Rabbit Anti-BRMS-1 Polyclonal Antibody

Product Specifications

Background

BRMS1 reduces the metastatic potential, but not the tumorogenicity, of human breast cancer and melanoma cell lines. The protein (breast cancer metastasis suppressor 1) encoded by BRMS1 localizes primarily to the nucleus and is a component of the mSin3a family of histone deacetylase complexes (HDAC) . The protein contains two coiled-coil motifs and several imperfect leucine zipper motifs. Alternative splicing results in two transcript variants encoding different isoforms.

CAS Number

9007-83-4

Product Name Alternative

BRMS1; Breast cancer metastasis-suppressor 1

Gene ID

25855

Accession Number

Q9HCU9

Reactivity

Human, Mouse, Rat

Immunogen

Synthesized peptide derived from the Internal region of human BRMS-1 at AA range: 40-120

Clonality

Polyclonal

Tag

Breast cancer metastasis-suppressor 1

Applications

WB, IHC, IF, ELISA

Purification Method

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration

1 mg/ml

Molecular Weight

28kD

Precautions

The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.

Shipping Conditions

Gel pack with blue ice.

Storage Conditions

Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Notes

BRMS-1 Polyclonal Antibody detects endogenous levels of BRMS-1 protein.

Observed Molecular Weight

Formulation

Liquid solution

Buffer pH

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Applications Notes

Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-1:2000; IHC 1:100-1:300; ELISA 1:20000; IF 1:50-200